• Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.

Functionally Immortalized Lung Epithelial Cells

The investigation of the human lung and its diseases is an important issue for drug development processes, although it is hampered by the availability of suitable in vitro models. Using our CI-SCREEN technology (recently published in Nature Communications; Lipps et al., 2018) we developed a novel immortal human lung epithelial cell line displaying a primary like phenotype.

Specifications of CI-huAEC

  • Characteristic expression of epithelial cell markers (e.g. E-Cadherin, ZO-1)
  • Maintained polarity
  • Tight barrier formation
  • Low permeability

Following assays have been performed and validated with the CI-huAEC cell line:

  • Transepithelial Electrical Resistance (TEER)-formation
  • Rhodamine permeation
  • GPCR profiling (cAMP regulation/Ca2+ regulation)
  • TGF-beta stimulation
Product Name Cat. No. Information Price
CI-huAEC,
Human Airway Epithelial cells
INS-CI-1011 Data sheet Get prices
Related Products
Product Name Cat. No. Size Price
huAEC Medium (ready-to-use) INS-ME-1013-100ml 100 ml € 75.00
huAEC Medium (ready-to-use) INS-ME-1013-500ml 500 ml € 290.00
huAEC Coating solution INS-SU-1018 20 ml € 40.00
huAEC Coating solution INS-SU-1018-100ml 5x20 ml € 160.00
Freezing medium INS-SU-1004 30 ml € 29.20

Related Protocols for Cultivation of CI-huAEC