• Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.

Literature

Genetic aspects of cell line development from a synthetic biology perspective. Botezatu L, Sievers S, Gama-Norton L, Schucht R, Hauser H, Wirth D. Adv Biochem Eng Biotechnol. 2012
http://www.ncbi.nlm.nih.gov/pubmed/22068842

Rapid establishment of g-protein-coupled receptor-expressing cell lines by site-specific integration. Schucht R, Lydford S, Andzinski L, Zauers J, Cooper J, Hauser H, Wirth D, May T. J Biomol Screen. 2011
http://www.ncbi.nlm.nih.gov/pubmed/21335600

Integrated strategy for the production of therapeutic retroviral vectors. Carrondo M, Panet A, Wirth D, Coroadinha AS, Cruz P, Falk H, Schucht R, Dupont F, Geny-Fiamma C, Merten OW, Hauser H. Hum Gene Ther. 2011
http://www.ncbi.nlm.nih.gov/pubmed/21043806

Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines. Gama-Norton L, Herrmann S, Schucht R, Coroadinha AS, Löw R, Alves PM, Bartholomae CC, Schmidt M, Baum C, Schambach A, Hauser H, Wirth D. Hum Gene Ther. 2010
http://www.ncbi.nlm.nih.gov/pubmed/20222806

Recombinant protein expression by targeting pre-selected chromosomal loci. Nehlsen K, Schucht R, da Gama-Norton L, Krömer W, Baer A, Cayli A, Hauser H, Wirth D. BMC Biotechnol. 2009
http://www.ncbi.nlm.nih.gov/pubmed/20003421

Precise regulation of transgene expression level and control of cell physiology. Schucht R, Wirth D, May T. Cell Biol Toxicol. 2009
http://www.ncbi.nlm.nih.gov/pubmed/19763851

Road to precision: recombinase-based targeting technologies for genome engineering. Wirth D, Gama-Norton L, Riemer P, Sandhu U, Schucht R, Hauser H. Curr Opin Biotechnol. 2007
http://www.ncbi.nlm.nih.gov/pubmed/17904350

A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors. Schucht R, Coroadinha AS, Zanta-Boussif MA, Verhoeyen E, Carrondo MJ, Hauser H, Wirth D. Mol Ther. 2006
http://www.ncbi.nlm.nih.gov/pubmed/16697259