• Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.

  • Rebuilding Nature. Rebuilding Life.


Genetic aspects of cell line development from a synthetic biology perspective. Botezatu L, Sievers S, Gama-Norton L, Schucht R, Hauser H, Wirth D. Adv Biochem Eng Biotechnol. 2012

Rapid establishment of g-protein-coupled receptor-expressing cell lines by site-specific integration. Schucht R, Lydford S, Andzinski L, Zauers J, Cooper J, Hauser H, Wirth D, May T. J Biomol Screen. 2011

Integrated strategy for the production of therapeutic retroviral vectors. Carrondo M, Panet A, Wirth D, Coroadinha AS, Cruz P, Falk H, Schucht R, Dupont F, Geny-Fiamma C, Merten OW, Hauser H. Hum Gene Ther. 2011

Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines. Gama-Norton L, Herrmann S, Schucht R, Coroadinha AS, Löw R, Alves PM, Bartholomae CC, Schmidt M, Baum C, Schambach A, Hauser H, Wirth D. Hum Gene Ther. 2010

Recombinant protein expression by targeting pre-selected chromosomal loci. Nehlsen K, Schucht R, da Gama-Norton L, Krömer W, Baer A, Cayli A, Hauser H, Wirth D. BMC Biotechnol. 2009

Precise regulation of transgene expression level and control of cell physiology. Schucht R, Wirth D, May T. Cell Biol Toxicol. 2009

Road to precision: recombinase-based targeting technologies for genome engineering. Wirth D, Gama-Norton L, Riemer P, Sandhu U, Schucht R, Hauser H. Curr Opin Biotechnol. 2007

A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors. Schucht R, Coroadinha AS, Zanta-Boussif MA, Verhoeyen E, Carrondo MJ, Hauser H, Wirth D. Mol Ther. 2006